Phase 1. Management of works
Ethics and veterinary project approvals
Phase 2. In vivo investigations of pharmacological and therapeutic long-term donepezil- JWH-133 co-treatment associations in Alzheimer’s disease
Prolonged oral donepezil- CB2 specific agonist JWH-133 co-treatment
Neuroimaging evaluation of cerebral metabolism
Biochemical and immunohistochemistry analysis
Phase 3. Implementation and Clinical Exploitation Strategies
Preliminary feasibility and impact study of donepezil-CB2 specific agonist JWH-133 co-treatment on future clinical exploitation strategies