Phase 1. Management of works

                 Ethics and veterinary project approvals

Phase 2. In vivo investigations of pharmacological and therapeutic long-term donepezil- JWH-133 co-treatment associations in Alzheimer’s disease

               Prolonged oral donepezil- CB2 specific agonist JWH-133 co-treatment

               Neuroimaging evaluation of cerebral metabolism

               Biochemical and immunohistochemistry analysis

Phase 3. Implementation and Clinical Exploitation Strategies 

             Preliminary feasibility and impact study of donepezil-CB2 specific agonist JWH-133 co-treatment on future clinical exploitation strategies